SMAD2/SMAD3 Polyclonal Antibody (CAB7536)
- SKU:
- CAB7536
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | SMAD2/SMAD3 Polyclonal Antibody |
| Product Code: | CAB7536 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IHC-P, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T |
| Cellular Location: | Cytoplasm, Nucleus |
| Customer Validation: | WB(Mus musculus, Homo sapiens, Gallus gallus, Rattus norvegicus) IHC(Mus musculus) IF(Gallus gallus)IHC(Mus musculus) |
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 150-250 of human SMAD2/SMAD3 (NP_005892.1). |
| Sequence: | EYAFN LKKDE VCVNP YHYQR VETPV LPPVL VPRHT EILTE LPPLD DYTHS IPENT NFPAG IEPQS NYIPE TPPPG YISED GETSD QQLNQ SMDTG SPAEL S |
| Synonyms: | HSPC193, HsT17436, JV15-2, LDS1C, LDS3, MADH3 |
| Calculated MW: | 48kDa/52kDa/25kDa/35kDa/43kDa |
| Observed MW: | 60kDa |
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