Smac/Diablo Monoclonal Antibody
- SKU:
- CAB23444
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | Smac/Diablo Monoclonal Antibody |
| Product Code: | CAB23444 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC50504 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, 293T, Hep G2, SGC-7901, Mouse testis |
| Cellular Location: | Mitochondrion |
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 56-239 of human Smac/Diablo (NP_063940.1). |
| Sequence: | AVPIA QKSEP HSLSS EALMR RAVSL VTDST STFLS QTTYA LIEAI TEYTK AVYTL TSLYR QYTSL LGKMN SEEED EVWQV IIGAR AEMTS KHQEY LKLET TWMTA VGLSE MAAEA AYQTG ADQAS ITARN HIQLV KLQVE EVHQL SRKAE TKLAE AQIEE LRQKT QEEGE ERAES EQEAY LRED |
| Synonyms: | SMAC, DFNA64 |
| Calculated MW: | 27kDa |
| Observed MW: | 22kDa |
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