SLC9A7 Antibody (PACO18907)
- SKU:
- PACO18907
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC9A7 Antibody (PACO18907) |
| Antibody SKU: | PACO18907 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human SLC9A7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO18907(SLC9A7 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. |
| Synonyms: | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| UniProt Protein Function: | SOX8: May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3'.Protein type: DNA-bindingChromosomal Location of Human Ortholog: 16p13.3Cellular Component: cytoplasm; nucleusMolecular Function: DNA binding; protein heterodimerization activity; transcription factor bindingBiological Process: negative regulation of photoreceptor cell differentiation; transcription from RNA polymerase II promoter; fat cell differentiation; cell fate commitment; positive regulation of gliogenesis; in utero embryonic development; astrocyte fate commitment; positive regulation of transcription, DNA-dependent; male gonad development; cell maturation; signal transduction; Sertoli cell development; enteric nervous system development; peripheral nervous system development; osteoblast differentiation; retina development in camera-type eye; positive regulation of osteoblast proliferation; oligodendrocyte differentiation; spermatogenesis; positive regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; negative regulation of myoblast differentiation; neural crest cell migration; negative regulation of apoptosis |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012] |
| UniProt Code: | Q96T83 |
| NCBI GenInfo Identifier: | 14211919 |
| NCBI Gene ID: | 84679 |
| NCBI Accession: | NP_115980.1 |
| UniProt Secondary Accession: | Q96T83,O75827, Q5JXP9 |
| UniProt Related Accession: | Q96T83 |
| Molecular Weight: | 80,131 Da |
| NCBI Full Name: | sodium/hydrogen exchanger 7 isoform 2 |
| NCBI Synonym Full Names: | solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7 |
| NCBI Official Symbol: | SLC9A7 |
| NCBI Official Synonym Symbols: | NHE7; NHE-7; SLC9A6 |
| NCBI Protein Information: | sodium/hydrogen exchanger 7; Na(+)/H(+) exchanger 7; nonselective sodium potassium/proton exchanger; solute carrier family 9 (sodium/hydrogen exchanger), isoform 7 |
| UniProt Protein Name: | Transcription factor SOX-8 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Transcription factor |
| UniProt Gene Name: | SOX8 |
| UniProt Entry Name: | SOX8_HUMAN |
| Antibodies |
| SLC9A7 Antibody (PACO05534) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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