SLC6A4 Polyclonal Antibody
- SKU:
- CAB23887
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SLC6A4 Polyclonal Antibody |
| Product Code: | CAB23887 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse brain, Rat brain |
| Cellular Location: | Cell membrane, Endomembrane system, Endosome membrane, Multi-pass membrane protein |
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.
| Immunogen: | Recombinant protein of human SLC6A4. |
| Sequence: | AVLTV ALIEA VAVSW FYGIT QFCRD VKEML GFSPG WFWRI CWVAI SPLFL LFIIC SFLMS PPQLR LFQYN YPYWS IILGY CIGTS SFICI PTYIA YRLII TPGTF KERII KSITP ETPTE IPCGD IRLNA V |
| Synonyms: | HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR |
| Calculated MW: | 70kDa |
| Observed MW: | 75kDa |
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