SLC51A Antibody (PACO47978)
- SKU:
- PACO47978
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC51A Antibody (PACO47978) |
| Antibody SKU: | PACO47978 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Organic solute transporter subunit α protein (1-48AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO47978 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO47978 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Essential component of the Ost-alpha/Ost-β complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid, export from enterocytes into portal blood. Efficiently transports the major species of bile acid,. |
| Synonyms: | Organic solute transporter subunit α (OST-alpha) (Solute carrier family 51 subunit alpha), SLC51A, OSTA |
| UniProt Protein Function: | OSTalpha: Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. Belongs to the OST-alpha family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 3q29Cellular Component: endoplasmic reticulum membrane; integral to membrane; plasma membrane; protein complexMolecular Function: protein heterodimerization activity; protein homodimerization activity; transporter activityBiological Process: bile acid and bile salt transport; transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86UW1 |
| NCBI GenInfo Identifier: | 217035113 |
| NCBI Gene ID: | 200931 |
| NCBI Accession: | NP_689885.4 |
| UniProt Secondary Accession: | Q86UW1,Q6ZMC7 |
| UniProt Related Accession: | Q86UW1 |
| Molecular Weight: | 38 kDa (MW of target protein) |
| NCBI Full Name: | organic solute transporter subunit alpha |
| NCBI Synonym Full Names: | solute carrier family 51, alpha subunit |
| NCBI Official Symbol: | SLC51A |
| NCBI Official Synonym Symbols: | OSTA; OSTalpha |
| NCBI Protein Information: | organic solute transporter subunit alpha |
| UniProt Protein Name: | Organic solute transporter subunit alpha |
| UniProt Synonym Protein Names: | Solute carrier family 51 subunit alpha |
| Protein Family: | |
| UniProt Gene Name: | SLC51A |
| UniProt Entry Name: | OSTA_HUMAN |
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