Antibody Name:	SLC41A2 Antibody (PACO20509)
Antibody SKU:	PACO20509
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, IHC
Recommended Dilutions:	ELISA:1:1000-1:2000, IHC:1:25-1:100
Species Reactivity:	Human
Immunogen:	Synthetic peptide of human SLC41A2

Form:	Liquid
Storage Buffer:	-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:	Antigen affinity purification
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO20509(SLC41A2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).
	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20509(SLC41A2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200).

Background:

SLC41A2 (solute carrier family 41, member 2), also known as SLC41A1-L, is a 573 amino acid, multi-pass membrane protein that belongs to the SLC41A transporter family that includes SLC41A1 and SLC41A3. Expressed in lymphocytes and localizing to the cell membrane, SLC41A2 contains twelve transmembrane domains, three myristoylation sequences, numerous possible phosphorylation sites and a putative N-glycosylation site. SLC41A2 is believed to function as a plasma-membrane magnesium transporter. Magnesium, a cofactor for ATP, plays a vital role in metabolic and biochemical processes.

Synonyms:

solute carrier family 41 (magnesium transporter), member 2

UniProt Protein Function:	SLC41A2: Acts as a plasma-membrane magnesium transporter. Belongs to the SLC41A transporter family.Protein type: Transporter; Membrane protein, integral; Transporter, SLC family; Channel, cation; Membrane protein, multi-passChromosomal Location of Human Ortholog: 12q23.3Cellular Component: plasma membraneMolecular Function: magnesium ion transmembrane transporter activity; protein bindingBiological Process: transmembrane transport
UniProt Protein Details:
NCBI Summary:
UniProt Code:	Q96JW4
NCBI GenInfo Identifier:	152112286
NCBI Gene ID:	84102
NCBI Accession:	Q96JW4.2
UniProt Secondary Accession:	Q96JW4,Q3KP68, Q9H0E5
UniProt Related Accession:	Q96JW4
Molecular Weight:	62,473 Da
NCBI Full Name:	Solute carrier family 41 member 2
NCBI Synonym Full Names:	solute carrier family 41 member 2
NCBI Official Symbol:	SLC41A2
NCBI Official Synonym Symbols:	SLC41A1-L1
NCBI Protein Information:	solute carrier family 41 member 2
UniProt Protein Name:	Solute carrier family 41 member 2
UniProt Synonym Protein Names:
Protein Family:	Solute carrier family
UniProt Gene Name:	SLC41A2
UniProt Entry Name:	S41A2_HUMAN