SLC41A1 Antibody (PACO59217)
- SKU:
- PACO59217
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC41A1 Antibody (PACO59217) |
| Antibody SKU: | PACO59217 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Solute carrier family 41 member 1 protein (1-96AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO59217 diluted at 1:400 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of HepG2 cells with PACO59217 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Acts as a magnesium transporter that is responsive to magnesium balance. |
| Synonyms: | Solute carrier family 41 member 1, SLC41A1 |
| UniProt Protein Function: | SLC41A1: Acts as a magnesium transporter that is responsive to magnesium balance. Belongs to the SLC41A transporter family.Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC familyChromosomal Location of Human Ortholog: 1q32.1Cellular Component: integral to membrane; plasma membraneMolecular Function: cation transmembrane transporter activityBiological Process: transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IVJ1 |
| NCBI GenInfo Identifier: | 51702206 |
| NCBI Gene ID: | 254428 |
| NCBI Accession: | NP_776253.3 |
| UniProt Secondary Accession: | Q8IVJ1,Q63HJ4, Q658Z5, Q659A4, Q6MZK2 |
| UniProt Related Accession: | Q8IVJ1 |
| Molecular Weight: | 55 kDa (MW of target protein) |
| NCBI Full Name: | solute carrier family 41 member 1 |
| NCBI Synonym Full Names: | solute carrier family 41 (magnesium transporter), member 1 |
| NCBI Official Symbol: | SLC41A1 |
| NCBI Official Synonym Symbols: | MgtE |
| NCBI Protein Information: | solute carrier family 41 member 1 |
| UniProt Protein Name: | Solute carrier family 41 member 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC41A1 |
| UniProt Entry Name: | S41A1_HUMAN |
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