SLC39A8 Polyclonal Antibody
- SKU:
- CAB22238
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SLC39A8 Polyclonal Antibody |
| Product Code: | CAB22238 |
| Reactivity: | Human, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | U-937, Rat liver |
| Cellular Location: | apical plasma membrane, basolateral plasma membrane, plasma membrane |
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human SLC39A8 (NP_071437.3). |
| Sequence: | MAPGR AVAGL LLLAA AGLGG VAEGP GLAFS EDVLS VFGAN LSLSA AQLQH LLEQM GAASR VGVPE PGQLH FNQCL TAEEI FSLHG FSNAT QITSS KFSVI |
| Synonyms: | ZIP8, CDG2N, PP3105, BIGM103, LZT-Hs6 |
| Calculated MW: | 50kDa |
| Observed MW: | 65kDa/130kDa |
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