SLC39A3 Antibody (PACO20504)
- SKU:
- PACO20504
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC39A3 Antibody (PACO20504) |
| Antibody SKU: | PACO20504 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:20-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human SLC39A3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO20504(SLC39A3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | SLC39A3 (solute carrier family 39, member 2), is a 314 amino acid, acid, multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters. Two isoforms of ZIP3 exist as a result of alternative splicing events. ZIP3 is involved in translocation of extracellular zinc into a variety of cell types. Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells. Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3. |
| Synonyms: | solute carrier family 39 (zinc transporter), member 3 |
| UniProt Protein Function: | SLC39A3: Acts as a zinc-influx transporter (Potential). Belongs to the ZIP transporter (TC 2.A.5) family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.3Cellular Component: plasma membraneMolecular Function: zinc ion transmembrane transporter activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9BRY0 |
| NCBI GenInfo Identifier: | 74732942 |
| NCBI Gene ID: | 29985 |
| NCBI Accession: | Q9BRY0.2 |
| UniProt Secondary Accession: | Q9BRY0,Q8WUG1, B3KMJ3 |
| UniProt Related Accession: | Q9BRY0 |
| Molecular Weight: | 11,459 Da |
| NCBI Full Name: | Zinc transporter ZIP3 |
| NCBI Synonym Full Names: | solute carrier family 39 member 3 |
| NCBI Official Symbol: | SLC39A3 |
| NCBI Official Synonym Symbols: | ZIP3; ZIP-3 |
| NCBI Protein Information: | zinc transporter ZIP3 |
| UniProt Protein Name: | Zinc transporter ZIP3 |
| UniProt Synonym Protein Names: | Solute carrier family 39 member 3; Zrt- and Irt-like protein 3; ZIP-3 |
| Protein Family: | Zinc transporter |
| UniProt Gene Name: | SLC39A3 |
| UniProt Entry Name: | S39A3_HUMAN |
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