SLC25A36 Antibody (PACO39810)
- SKU:
- PACO39810
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC25A36 Antibody (PACO39810) |
| Antibody SKU: | PACO39810 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Solute carrier family 25 member 36 protein (58-110AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: SLC25A36 antibody at 4µg/ml. Lane 1: A431 whole cell lysate. Lane 2: A549 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 35, 15, 18 kDa. Observed band size: 35 kDa. |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO39810 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO39810 at dilution of 1:100. |
| Background: | Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism. Also transports guanine but not adenine (deoxy)nucleotides. Is inhibited strongly by pyridoxal 5'-phosphate, 4,7-diphenyl-1,10-phenanthroline, tannic acid, and mercurials (mercury dichloride, Mersalyl acid, p-hydroxymercuribenzoate). Participates in mitochondrial genome maintenance, regulation of mitochondrial membrane potential and mitochondrial respiration. |
| Synonyms: | Solute carrier family 25 member 36, SLC25A36 |
| UniProt Protein Function: | SLC25A36: Belongs to the mitochondrial carrier family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Mitochondrial; Transporter, SLC family; Membrane protein, integral; TransporterChromosomal Location of Human Ortholog: 3q23Cellular Component: integral to membrane; mitochondrial inner membrane; mitochondrionMolecular Function: pyrimidine nucleotide transmembrane transporter activity; structural constituent of ribosomeBiological Process: mitochondrial genome maintenance; mitochondrion organization and biogenesis; pyrimidine nucleotide transport; regulation of mitochondrial membrane potential; translation; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96CQ1 |
| NCBI GenInfo Identifier: | 157388989 |
| NCBI Gene ID: | 55186 |
| NCBI Accession: | NP_001098117.1 |
| UniProt Secondary Accession: | Q96CQ1,Q05CY1, Q9H0G8, Q9NVN5, A8MYF7 |
| UniProt Related Accession: | Q96CQ1 |
| Molecular Weight: | 17,358 Da |
| NCBI Full Name: | solute carrier family 25 member 36 isoform a |
| NCBI Synonym Full Names: | solute carrier family 25 member 36 |
| NCBI Official Symbol: | SLC25A36 |
| NCBI Official Synonym Symbols: | PNC2 |
| NCBI Protein Information: | solute carrier family 25 member 36 |
| UniProt Protein Name: | Solute carrier family 25 member 36 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC25A36 |
| UniProt Entry Name: | S2536_HUMAN |
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