Description
| Antibody Name: | SLC25A25 Antibody (PACO37066) |
| Antibody SKU: | PACO37066 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Calcium-binding mitochondrial carrier protein SCaMC-2 protein (1-189AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: SLC25A25 antibody at 10µg/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 53, 56, 57, 55, 41 kDa. Observed band size: 53 kDa. |
![]() | Immunofluorescent analysis of U251 cells using PACO37066 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37066 at dilution of 1:100. |
| Background: | Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. |
| Synonyms: | Calcium-binding mitochondrial carrier protein SCaMC-2 (Mitochondrial ATP-Mg/Pi carrier protein 3) (Mitochondrial Ca(2+)-dependent solute carrier protein 3) (Small calcium-binding mitochondrial carrier protein 2) (Solute carrier family 25 member 25), SLC25A25, APC3 KIAA1896 MCSC3 SCAMC2 |
| UniProt Protein Function: | SLC25A25: Calcium-dependent mitochondrial solute carrier. Mitochondrial solute carriers shuttle metabolites, nucleotides, and cofactors through the mitochondrial inner membrane. May act as a ATP-Mg/Pi exchanger that mediates the transport of Mg-ATP in exchange for phosphate, catalyzing the net uptake or efflux of adenine nucleotides into or from the mitochondria. Belongs to the mitochondrial carrier family. 6 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter; Mitochondrial; Transporter, SLC family; Membrane protein, integral Chromosomal Location of Human Ortholog: 9q34.11 Cellular Component: mitochondrion; intracellular membrane-bound organelle; mitochondrial inner membrane; integral to membrane Molecular Function:calcium ion binding Biological Process: ATP metabolic process; response to food; response to dietary excess; camera-type eye development; multicellular organism growth; cellular respiration; response to activity |
| NCBI Summary: | The protein encoded by this gene belongs to the family of calcium-binding mitochondrial carriers, with a characteristic mitochondrial carrier domain at the C-terminus. These proteins are found in the inner membranes of mitochondria, and function as transport proteins. They shuttle metabolites, nucleotides and cofactors through the mitochondrial membrane and thereby connect and/or regulate cytoplasm and matrix functions. This protein may function as an ATP-Mg/Pi carrier that mediates the transport of Mg-ATP in exchange for phosphate, and likely responsible for the net uptake or efflux of adenine nucleotides into or from the mitochondria. Alternatively spliced transcript variants encoding different isoforms with a common C-terminus but variable N-termini have been described for this gene. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q6KCM7 |
| NCBI GenInfo Identifier: | 74758042 |
| NCBI Gene ID: | 114789 |
| NCBI Accession: | Q6KCM7.1 |
| UniProt Secondary Accession: | Q6KCM7,Q5SYW7, Q5SYW8, Q5SYX3, Q5VWU2, Q5VWU3, Q5VWU4 Q6KCM4, Q6KCM6, Q6UX48, Q705K2, Q96PZ1, |
| UniProt Related Accession: | Q6KCM7 |
| Molecular Weight: | 469 |
| NCBI Full Name: | Calcium-binding mitochondrial carrier protein SCaMC-2 |
| NCBI Synonym Full Names: | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 |
| NCBI Official Symbol: | SLC25A25 |
| NCBI Official Synonym Symbols: | MCSC; PCSCL; SCAMC-2 |
| NCBI Protein Information: | calcium-binding mitochondrial carrier protein SCaMC-2; mitochondrial ATP-Mg/Pi carrier protein 3; short calcium-binding mitochondrial carrier 2; small calcium-binding mitochondrial carrier 2; solute carrier family 25, member 25, isoform a; mitochondrial Ca(2+)-dependent solute carrier protein 3 |
| UniProt Protein Name: | Calcium-binding mitochondrial carrier protein SCaMC-2 |
| UniProt Synonym Protein Names: | Mitochondrial ATP-Mg/Pi carrier protein 3; Mitochondrial Ca(2+)-dependent solute carrier protein 3; Small calcium-binding mitochondrial carrier protein 2; Solute carrier family 25 member 25 |
| Protein Family: | Calcium-binding mitochondrial carrier protein |
| UniProt Gene Name: | SLC25A25 |
| UniProt Entry Name: | SCMC2_HUMAN |
| Antibodies |
| SLC25A25 Antibody (PACO12268) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Additional Information
Product Type: |
Antibody |
Reactivity: |
Human |
Reactivity: |
Mouse |
Host Species: |
Rabbit |
Isotype: |
IgG |
Applications: |
ELISA |
Applications: |
WB |
Applications: |
IHC |
Applications: |
IF |
Antibody Type: |
Polyclonal Antibody |
Conjugation: |
Unconjugated |


