SLC25A21 Antibody (PACO23449)
- SKU:
- PACO23449
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC25A21 Antibody (PACO23449) |
| Antibody SKU: | PACO23449 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human SLC25A21. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HepG2 cells, using SLC25A21 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using SLC25A21 antibody. |
| Background: | Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2-oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate. |
| Synonyms: | mgc126570; odc; odc1; oxodicarboxylate carrier; slc25a21 |
| UniProt Protein Function: | SLC25A21: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate. Belongs to the mitochondrial carrier family.Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Mitochondrial; Transporter, SLC familyChromosomal Location of Human Ortholog: 14q11.2Cellular Component: mitochondrial inner membrane; integral to membraneBiological Process: lysine catabolic process; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9BQT8 |
| NCBI GenInfo Identifier: | 283837920 |
| NCBI Gene ID: | 89874 |
| NCBI Accession: | NP_001164641.1 |
| UniProt Secondary Accession: | Q9BQT8 |
| UniProt Related Accession: | Q9BQT8 |
| Molecular Weight: | |
| NCBI Full Name: | mitochondrial 2-oxodicarboxylate carrier isoform 2 |
| NCBI Synonym Full Names: | solute carrier family 25 member 21 |
| NCBI Official Symbol: | SLC25A21 |
| NCBI Official Synonym Symbols: | ODC; ODC1 |
| NCBI Protein Information: | mitochondrial 2-oxodicarboxylate carrier |
| UniProt Protein Name: | Mitochondrial 2-oxodicarboxylate carrier |
| UniProt Synonym Protein Names: | Solute carrier family 25 member 21 |
| Protein Family: | Probable ornithine decarboxylase |
| UniProt Gene Name: | SLC25A21 |
| UniProt Entry Name: | ODC_HUMAN |
| Antibodies |
| SLC25A21 Antibody (PACO01200) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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