Description
| Antibody Name: | SLC25A21 Antibody |
| Antibody SKU: | PACO01200 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human ODC. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | SLC25A21; ODC; Mitochondrial 2-oxodicarboxylate carrier; Solute carrier family 25 member 21 |
| UniProt Protein Function: | SLC25A21: Transports C5-C7 oxodicarboxylates across the inner membranes of mitochondria. Can transport 2-oxoadipate, 2- oxoglutarate, adipate, glutarate, and to a lesser extent, pimelate, 2-oxopimelate, 2-aminoadipate, oxaloacetate, and citrate. Belongs to the mitochondrial carrier family.Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Mitochondrial; Transporter, SLC familyChromosomal Location of Human Ortholog: 14q11.2Cellular Component: mitochondrial inner membrane; integral to membraneBiological Process: lysine catabolic process; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | SLC25A21 is a homolog of the S. cerevisiae ODC proteins, mitochondrial carriers that transport C5-C7 oxodicarboxylates across inner mitochondrial membranes. One of the species transported by ODC is 2-oxoadipate, a common intermediate in the catabolism of lysine, tryptophan, and hydroxylysine in mammals. Within mitochondria, 2-oxoadipate is converted into acetyl-CoA.[supplied by OMIM, Apr 2004] |
| UniProt Code: | Q9BQT8 |
| NCBI GenInfo Identifier: | 283837920 |
| NCBI Gene ID: | 89874 |
| NCBI Accession: | NP_001164641.1 |
| UniProt Secondary Accession: | Q9BQT8 |
| UniProt Related Accession: | Q9BQT8 |
| Molecular Weight: | |
| NCBI Full Name: | mitochondrial 2-oxodicarboxylate carrier isoform 2 |
| NCBI Synonym Full Names: | solute carrier family 25 member 21 |
| NCBI Official Symbol: | SLC25A21 |
| NCBI Official Synonym Symbols: | ODC; ODC1 |
| NCBI Protein Information: | mitochondrial 2-oxodicarboxylate carrier |
| UniProt Protein Name: | Mitochondrial 2-oxodicarboxylate carrier |
| UniProt Synonym Protein Names: | Solute carrier family 25 member 21 |
| Protein Family: | Probable ornithine decarboxylase |
| UniProt Gene Name: | SLC25A21 |
| UniProt Entry Name: | ODC_HUMAN |