Description
Antibody Name: | SLC25A10 Antibody (PACO47162) |
Antibody SKU: | PACO47162 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Recombinant Human Mitochondrial dicarboxylate carrier protein (124-162AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: SLC25A10 antibody at 16µg/ml. Lane 1: Mouse liver tissue. Lane 2: Mouse kidney tissue. Lane 3: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 32, 33 kDa. Observed band size: 32, 24 kDa.. |
![]() | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO47162 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human liver tissue using PACO47162 at dilution of 1:100. |
Background: | Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane. |
Synonyms: | Mitochondrial dicarboxylate carrier (Solute carrier family 25 member 10), SLC25A10, DIC |
UniProt Protein Function: | SLC25A10: Involved in translocation of malonate, malate and succinate in exchange for phosphate, sulfate, sulfite or thiosulfate across mitochondrial inner membrane. Belongs to the mitochondrial carrier family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter, SLC family; Membrane protein, multi-pass; Transporter; Membrane protein, integral; MitochondrialChromosomal Location of Human Ortholog: 17q25.3Cellular Component: mitochondrial inner membrane; integral to membrane; nucleusMolecular Function: protein binding; dicarboxylic acid transmembrane transporter activityBiological Process: sulfur amino acid metabolic process; dicarboxylic acid transport; sulfur amino acid catabolic process; carbohydrate metabolic process; glucose metabolic process; ion transport; pathogenesis; transmembrane transport; mitochondrial transport; gluconeogenesis |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012] |
UniProt Code: | Q9UBX3 |
NCBI GenInfo Identifier: | 20137671 |
NCBI Gene ID: | 1468 |
NCBI Accession: | Q9UBX3.2 |
UniProt Secondary Accession: | Q9UBX3 |
UniProt Related Accession: | Q9UBX3 |
Molecular Weight: | Predicted Molecular Mass: 60.6kDaAccurate Molecular Mass: 61kDa |
NCBI Full Name: | Mitochondrial dicarboxylate carrier |
NCBI Synonym Full Names: | solute carrier family 25 member 10 |
NCBI Official Symbol: | SLC25A10 |
NCBI Official Synonym Symbols: | DIC |
NCBI Protein Information: | mitochondrial dicarboxylate carrier |
UniProt Protein Name: | Mitochondrial dicarboxylate carrier |
UniProt Synonym Protein Names: | Solute carrier family 25 member 10 |
Protein Family: | |
UniProt Gene Name: | SLC25A10 |
UniProt Entry Name: | DIC_HUMAN |
Antibodies |
SLC25A10 Antibody (PACO12260) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |