SLC24A3 Antibody (PACO20484)
- SKU:
- PACO20484
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC24A3 Antibody (PACO20484) |
| Antibody SKU: | PACO20484 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthetic peptide of human SLC24A3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20484(SLC24A3 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions. |
| Synonyms: | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| UniProt Protein Function: | SLC24A3: Transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.Protein type: Membrane protein, multi-pass; Transporter, SLC family; Membrane protein, integral; TransporterChromosomal Location of Human Ortholog: 20p13Cellular Component: integral to plasma membrane; plasma membraneMolecular Function: calcium channel activity; calcium ion binding; calcium, potassium:sodium antiporter activity; potassium ion binding; sodium ion bindingBiological Process: cellular calcium ion homeostasis; ion transport |
| UniProt Protein Details: | |
| NCBI Summary: | Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9HC58 |
| NCBI GenInfo Identifier: | 116242671 |
| NCBI Gene ID: | 57419 |
| NCBI Accession: | Q9HC58.4 |
| UniProt Secondary Accession: | Q9HC58,Q9BQJ9, Q9BQL7, Q9BQY3, Q9H519, B1AKV7 |
| UniProt Related Accession: | Q9HC58 |
| Molecular Weight: | 71,992 Da |
| NCBI Full Name: | Sodium/potassium/calcium exchanger 3 |
| NCBI Synonym Full Names: | solute carrier family 24 member 3 |
| NCBI Official Symbol: | SLC24A3 |
| NCBI Official Synonym Symbols: | NCKX3 |
| NCBI Protein Information: | sodium/potassium/calcium exchanger 3 |
| UniProt Protein Name: | Sodium/potassium/calcium exchanger 3 |
| UniProt Synonym Protein Names: | Na(+)/K(+)/Ca(2+)-exchange protein 3; Solute carrier family 24 member 3 |
| Protein Family: | Sodium/potassium/calcium exchanger |
| UniProt Gene Name: | SLC24A3 |
| UniProt Entry Name: | NCKX3_HUMAN |
| Antibodies |
| SLC24A3 Antibody (PACO04811) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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