SLC16A8 Antibody (PACO51954)
- SKU:
- PACO51954
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC16A8 Antibody (PACO51954) |
| Antibody SKU: | PACO51954 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Monocarboxylate transporter 3 protein (432-504AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: K562 whole cell lysate, Jurkat whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue. All lanes: SLC16A8 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 53 kDa. Observed band size: 53 kDa.. |
 | Immunofluorescent analysis of A549 cells using PACO51954 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human eye tissue using PACO51954 at dilution of 1:100. |
| Background: | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acid, derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). |
| Synonyms: | Monocarboxylate transporter 3 (MCT 3) (Solute carrier family 16 member 8), SLC16A8, MCT3 |
| UniProt Protein Function: | SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q12.3-q13.2 Cellular Component: membrane; plasma membrane Molecular Function:lactate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity Biological Process: lactate transport; leukocyte migration; pyruvate metabolic process |
| NCBI Summary: | SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | O95907 |
| NCBI GenInfo Identifier: | 17433295 |
| NCBI Gene ID: | 23539 |
| NCBI Accession: | O95907.1 |
| UniProt Secondary Accession: | O95907,Q9UBE2, |
| UniProt Related Accession: | O95907 |
| Molecular Weight: | 52,319 Da |
| NCBI Full Name: | Monocarboxylate transporter 3 |
| NCBI Synonym Full Names: | solute carrier family 16 member 8 |
| NCBI Official Symbol: | SLC16A8 |
| NCBI Official Synonym Symbols: | MCT3; REMP |
| NCBI Protein Information: | monocarboxylate transporter 3 |
| UniProt Protein Name: | Monocarboxylate transporter 3 |
| UniProt Synonym Protein Names: | Solute carrier family 16 member 8 |
| Protein Family: | Monocarboxylate transporter |
| UniProt Gene Name: | SLC16A8 |
| UniProt Entry Name: | MOT3_HUMAN |
| ELISA Kits |
| Human SLC16A8 ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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