SLC16A8 Antibody (PACO20474)
- SKU:
- PACO20474
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC16A8 Antibody (PACO20474) |
| Antibody SKU: | PACO20474 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human SLC16A8 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: Human fetal brain tissue, Primary antibody: PACO20474(SLC16A8 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO20474(SLC16A8 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes. Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acid, derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. |
| Synonyms: | solute carrier family 16 (monocarboxylate transporter), member 8 |
| UniProt Protein Function: | SLC16A8: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. |
| UniProt Protein Details: | Protein type:Transporter, SLC family; Transporter; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 22q12.3-q13.2 Cellular Component: membrane; plasma membrane Molecular Function:lactate transmembrane transporter activity; monocarboxylic acid transmembrane transporter activity Biological Process: lactate transport; leukocyte migration; pyruvate metabolic process |
| NCBI Summary: | SLC16A8 is a member of a family of proton-coupled monocarboxylate transporters that mediate lactate transport across cell membranes (Yoon et al., 1999 [PubMed 10493836]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | O95907 |
| NCBI GenInfo Identifier: | 17433295 |
| NCBI Gene ID: | 23539 |
| NCBI Accession: | O95907.1 |
| UniProt Secondary Accession: | O95907,Q9UBE2, |
| UniProt Related Accession: | O95907 |
| Molecular Weight: | 52,319 Da |
| NCBI Full Name: | Monocarboxylate transporter 3 |
| NCBI Synonym Full Names: | solute carrier family 16 member 8 |
| NCBI Official Symbol: | SLC16A8 |
| NCBI Official Synonym Symbols: | MCT3; REMP |
| NCBI Protein Information: | monocarboxylate transporter 3 |
| UniProt Protein Name: | Monocarboxylate transporter 3 |
| UniProt Synonym Protein Names: | Solute carrier family 16 member 8 |
| Protein Family: | Monocarboxylate transporter |
| UniProt Gene Name: | SLC16A8 |
| UniProt Entry Name: | MOT3_HUMAN |
| ELISA Kits |
| Human SLC16A8 ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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