SLC16A11 Antibody (PACO61105)
- SKU:
- PACO61105
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC16A11 Antibody (PACO61105) |
| Antibody SKU: | PACO61105 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Monocarboxylate transporter 11 protein (428-471AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: A549 whole cell lysate, Hela whole cell lysate. All lanes: SLC16A11 antibody at 3.8µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 48 kDa. Observed band size: 48 kDa. |
 | Immunofluorescence staining of A549 cells with PACO61105 at 1:150, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane (Probable). Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids. |
| Synonyms: | Monocarboxylate transporter 11 (MCT 11) (Solute carrier family 16 member 11), SLC16A11, MCT11 |
| UniProt Protein Function: | SLC16A11: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates. Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.Protein type: Transporter, SLC family; Membrane protein, integral; Membrane protein, multi-pass; TransporterChromosomal Location of Human Ortholog: 17p13.1Cellular Component: endoplasmic reticulum membrane; integral to plasma membraneMolecular Function: lactate transmembrane transporter activityBiological Process: lipid metabolic process |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8NCK7 |
| NCBI GenInfo Identifier: | 74730153 |
| NCBI Gene ID: | 162515 |
| NCBI Accession: | Q8NCK7.1 |
| UniProt Secondary Accession: | Q8NCK7 |
| UniProt Related Accession: | Q8NCK7 |
| Molecular Weight: | 47,791 Da |
| NCBI Full Name: | Monocarboxylate transporter 11 |
| NCBI Synonym Full Names: | solute carrier family 16 member 11 |
| NCBI Official Symbol: | SLC16A11 |
| NCBI Official Synonym Symbols: | MCT11 |
| NCBI Protein Information: | monocarboxylate transporter 11 |
| UniProt Protein Name: | Monocarboxylate transporter 11 |
| UniProt Synonym Protein Names: | Solute carrier family 16 member 11 |
| Protein Family: | Monocarboxylate transporter |
| UniProt Gene Name: | SLC16A11 |
| UniProt Entry Name: | MOT11_HUMAN |
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