SLC13A5 Antibody (PACO50718)
- SKU:
- PACO50718
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC13A5 Antibody (PACO50718) |
| Antibody SKU: | PACO50718 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Recombinant Human Solute carrier family 13 member 5 protein (156-204AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: HepG2 whole cell lysate, Rat liver tissue, Mouse heart tissue. All lanes: SLC13A5 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 64, 59, 62 kDa. Observed band size: 64, 59 kDa.. |
 | Immunofluorescent analysis of HepG2 cells using PACO50718 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO50718 at dilution of 1:100. |
| Background: | High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acid, and cholesterol. |
| Synonyms: | Solute carrier family 13 member 5 (Na(+)/citrate cotransporter) (NaCT) (Sodium-coupled citrate transporter) (Sodium-dependent citrate transporter), SLC13A5, NACT |
| UniProt Protein Function: | SLC13A5: High-affinity sodium/citrate cotransporter that mediates citrate entry into cells. The transport process is electrogenic; it is the trivalent form of citrate rather than the divalent form that is recognized as a substrate. May facilitate the utilization of circulating citrate for the generation of metabolic energy and for the synthesis of fatty acids and cholesterol. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC familyChromosomal Location of Human Ortholog: 17p13.1Cellular Component: basolateral plasma membrane; integral to membrane; plasma membraneMolecular Function: citrate transmembrane transporter activity; succinate transmembrane transporter activity; sodium:dicarboxylate symporter activityBiological Process: citrate transport; sodium ion transport; transmembrane transportDisease: Epileptic Encephalopathy, Early Infantile, 25 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a protein belonging to the solute carrier family 13 group of proteins. This family member is a sodium-dependent citrate cotransporter that may regulate metabolic processes. Mutations in this gene cause early infantile epileptic encephalopathy 25. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014] |
| UniProt Code: | Q86YT5 |
| NCBI GenInfo Identifier: | 219802232 |
| NCBI Gene ID: | 284111 |
| NCBI Accession: | NP_001137310.1 |
| UniProt Secondary Accession: | Q86YT5,Q6ZMG1, B3KXR0, B7Z4P2, B7ZLB4, F8W7N2 |
| UniProt Related Accession: | Q86YT5 |
| Molecular Weight: | 58,092 Da |
| NCBI Full Name: | solute carrier family 13 member 5 isoform b |
| NCBI Synonym Full Names: | solute carrier family 13 (sodium-dependent citrate transporter), member 5 |
| NCBI Official Symbol: | SLC13A5 |
| NCBI Official Synonym Symbols: | NACT; mIndy; EIEE25 |
| NCBI Protein Information: | solute carrier family 13 member 5; Na(+)/citrate cotransporter; Na+-coupled citrate transporter protein; sodium-dependent dicarboxylate transporter |
| UniProt Protein Name: | Solute carrier family 13 member 5 |
| UniProt Synonym Protein Names: | Na(+)/citrate cotransporter; NaCT; Sodium-coupled citrate transporter; Sodium-dependent citrate transporter |
| Protein Family: | |
| UniProt Gene Name: | SLC13A5 |
| UniProt Entry Name: | S13A5_HUMAN |
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