SLC12A4 Antibody (PACO42534)
- SKU:
- PACO42534
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SLC12A4 Antibody (PACO42534) |
| Antibody SKU: | PACO42534 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Solute carrier family 12 member 4 protein (601-900AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO42534 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO42534 at dilution of 1:100. |
| Background: | Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia. Isoform 4 has no transport activity. |
| Synonyms: | Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1), SLC12A4, KCC1 |
| UniProt Protein Function: | KCC1: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia. Isoform 4 has no transport activity. Belongs to the SLC12A transporter family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Transporter; Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC familyChromosomal Location of Human Ortholog: 16q22.1Cellular Component: membrane; integral to plasma membrane; lysosomal membrane; plasma membraneMolecular Function: protein kinase binding; potassium:chloride symporter activityBiological Process: transport; ion transport; chloride transport; cell volume homeostasis; transmembrane transport; potassium ion transport |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2013] |
| UniProt Code: | Q9UP95 |
| NCBI GenInfo Identifier: | 27151691 |
| NCBI Gene ID: | 6560 |
| NCBI Accession: | Q9UP95.2 |
| UniProt Secondary Accession: | Q9UP95,O60632, O75893, Q13953, Q96LD5, B4DF69, B4DR04 B4DZ82, B7ZAV0, F5H066 |
| UniProt Related Accession: | Q9UP95 |
| Molecular Weight: | 1085 |
| NCBI Full Name: | Solute carrier family 12 member 4 |
| NCBI Synonym Full Names: | solute carrier family 12 (potassium/chloride transporter), member 4 |
| NCBI Official Symbol: | SLC12A4 |
| NCBI Official Synonym Symbols: | KCC1 |
| NCBI Protein Information: | solute carrier family 12 member 4; hKCC1; CTC-479C5.17; erythroid K-Cl cotransporter 1; potassium/chloride cotransporter 1; electroneutral potassium-chloride cotransporter 1; solute carrier family 12 (potassium/chloride transporters), member 4 |
| UniProt Protein Name: | Solute carrier family 12 member 4 |
| UniProt Synonym Protein Names: | Electroneutral potassium-chloride cotransporter 1; Erythroid K-Cl cotransporter 1; hKCC1 |
| Protein Family: | Solute carrier family |
| UniProt Gene Name: | SLC12A4 |
| UniProt Entry Name: | S12A4_HUMAN |
| Antibodies |
| SLC12A4 Antibody (PACO12239) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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