SIRT7 Polyclonal Antibody
- SKU:
- CAB21731
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SIRT7 Polyclonal Antibody |
| Product Code: | CAB21731 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, Mouse thymus, Rat thymus |
| Cellular Location: | Cytoplasm, Nucleus, nucleolus |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 201-400 of human SIRT7 (NP_057622.1). |
| Sequence: | NREYV RVFDV TERTA LHRHQ TGRTC HKCGT QLRDT IVHFG ERGTL GQPLN WEAAT EAASR ADTIL CLGSS LKVLK KYPRL WCMTK PPSRR PKLYI VNLQW TPKDD WAALK LHGKC DDVMR LLMAE LGLEI PAYSR WQDPI FSLAT PLRAG EEGSH SRKSL CRSRE EAPPG DRGAP LSSAP ILGGW FGRGC TKRTK RKKVT |
| Synonyms: | SIR2L7 |
| Calculated MW: | 45kDa |
| Observed MW: | 45kDa |
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