SIRT7 Monoclonal Antibody
- SKU:
- CAB22735
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SIRT7 Monoclonal Antibody |
| Product Code: | CAB22735 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC56567 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HepG2, Mouse thymus |
| Cellular Location: | Cytoplasm, Nucleus, nucleolus |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 301-400 of human SIRT7 (NP_057622.1). |
| Sequence: | TPKDD WAALK LHGKC DDVMR LLMAE LGLEI PAYSR WQDPI FSLAT PLRAG EEGSH SRKSL CRSRE EAPPG DRGAP LSSAP ILGGW FGRGC TKRTK RKKVT |
| Synonyms: | SIR2L7 |
| Calculated MW: | 45kDa |
| Observed MW: | 45kDa |
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