SIRT5 Monoclonal Antibody
- SKU:
- CAB23083
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SIRT5 Monoclonal Antibody |
| Product Code: | CAB23083 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC59763 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:1000-1:5000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293F, Mouse heart, Mouse liver, Rat heart, Rat liver |
| Cellular Location: | Cytoplasm, Mitochondrion, Mitochondrion intermembrane space, Mitochondrion matrix, Nucleus, cytosol |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 37-310 of human SIRT5 (NP_036373.1). |
| Sequence: | SSSMA DFRKF FAKAK HIVII SGAGV SAESG VPTFR GAGGY WRKWQ AQDLA TPLAF AHNPS RVWEF YHYRR EVMGS KEPNA GHRAI AECET RLGKQ GRRVV VITQN IDELH RKAGT KNLLE IHGSL FKTRC TSCGV VAENY KSPIC PALSG KGAPE PGTQD ASIPV EKLPR CEEAG CGGLL RPHVV WFGEN LDPAI LEEVD RELAH CDLCL VVGTS SVVYP AAMFA PQVAA RGVPV AEFNT ETTPA TNRFR FHFQG PCGTT LPEAL ACHEN ETVS |
| Synonyms: | SIR2L5 |
| Calculated MW: | 34kDa |
| Observed MW: | 34kDa |
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