SIRT3 Monoclonal Antibody
- SKU:
- CAB22409
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SIRT3 Monoclonal Antibody |
| Product Code: | CAB22409 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC51535 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Mitochondrion matrix |
SIRT3 encodes a member of the sirtuin family of class III histone deacetylases, homologs to the yeast Sir2 protein. The encoded protein is found exclusively in mitochondria, where it can eliminate reactive oxygen species, inhibit apoptosis, and prevent the formation of cancer cells. SIRT3 has far-reaching effects on nuclear gene expression, cancer, cardiovascular disease, neuroprotection, aging, and metabolic control.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-399 of human SIRT3 (NP_036371.1). |
| Sequence: | QRFLL HVVDF PMADL LLILG TSLEV EPFAS LTEAV RSSVP RLLIN RDLVG PLAWH PRSRD VAQLG DVVHG VESLV ELLGW TEEMR DLVQR ETGKL DGPDK |
| Synonyms: | SIR2L3 |
| Calculated MW: | 44kDa |
| Observed MW: | 28kDa |
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