SIGLEC14 Antibody (PACO20464)
- SKU:
- PACO20464
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SIGLEC14 Antibody (PACO20464) |
| Antibody SKU: | PACO20464 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human SIGLEC14 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20464(SIGLEC14 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO20464(SIGLEC14 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Putative adhesion molecule. Sialic acid, binding paired receptor which may activate associated receptors. Interacts with TYROBP. Mainly expressed in hematopoietic tissues including bone marrow, spleen and fetal liver. Siglec-14 is predominantly expressed in hematopoietic tissues but is also found in lung and testis. |
| Synonyms: | sialic acid, binding Ig-like lectin 14 |
| UniProt Protein Function: | SIGLEC14: Putative adhesion molecule. Sialic acid-binding paired receptor which may activate associated receptors. Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family. Interacts with TYROBPChromosomal Location of Human Ortholog: 19q13.4Cellular Component: plasma membraneBiological Process: innate immune response |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q08ET2 |
| NCBI GenInfo Identifier: | 121940125 |
| NCBI Gene ID: | 100049587 |
| NCBI Accession: | Q08ET2.1 |
| UniProt Secondary Accession: | Q08ET2,Q6UXG0 |
| UniProt Related Accession: | Q08ET2 |
| Molecular Weight: | 43,970 Da |
| NCBI Full Name: | Sialic acid-binding Ig-like lectin 14 |
| NCBI Synonym Full Names: | sialic acid binding Ig like lectin 14 |
| NCBI Official Symbol: | SIGLEC14 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | sialic acid-binding Ig-like lectin 14 |
| UniProt Protein Name: | Sialic acid-binding Ig-like lectin 14 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Sialic acid-binding Ig-like lectin |
| UniProt Gene Name: | SIGLEC14 |
| UniProt Entry Name: | SIG14_HUMAN |
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