SHMT1 Polyclonal Antibody
- SKU:
- CAB4113
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SHMT1 Polyclonal Antibody |
| Product Code: | CAB4113 |
| Reactivity: | Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse liver, Mouse kidney, Rat liver, Rat kidney |
| Cellular Location: | Cytoplasm |
| Customer Validation: | WB(Homo sapiens) |
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5, 10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 285-444 of human SHMT1 (NP_683718.1). |
| Sequence: | FKVYQ HQVVA NCRAL SEALT ELGYK IVTGG SDNHL ILVDL RSKGT DGGRA EKVLE ACSIA CNKNT CPGDR SALRP SGLRL GTPAL TSRGL LEKDF QKVAH FIHRG IELTL QIQSD TGVRA TLKEF KERLA GDKYQ AAVQA LREEV ESFAS LFPLP GLPDF |
| Synonyms: | SHMT, CSHMT |
| Calculated MW: | 53kDa |
| Observed MW: | 50kDa |
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Human SHMT1 Recombinant Protein (RPES4467)
Metabolism Recombinant Proteins
system_update_altDatasheetHuman SHMT1 Recombinant Protein Serine Hydroxymethyltransferase Cytosolic (SHMT1) is a member of the SHMT family. SHMT1 is a cytoplasmic protein and exists as a homotetr