SHMT1 Monoclonal Antibody [PAT26E5AT] (CPAB0234)
![SHMT1 Monoclonal Antibody [PAT26E5AT] (CPAB0234)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58459/63641/shmt1-monoclonal-antibody-pat26e5at-cpab0234__82470__75692.1706535018.jpg?c=1 "SHMT1 Monoclonal Antibody [PAT26E5AT] (CPAB0234)")
- SKU:
- CPAB0234
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT26E5AT
- Applications:
- WB
- Applications:
- ELISA
- Applications:
- FC
![SHMT1 Monoclonal Antibody [PAT26E5AT] (CPAB0234)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58459/63641/shmt1-monoclonal-antibody-pat26e5at-cpab0234__82470__75692.1706535018.jpg?c=1&imbypass=on "SHMT1 Monoclonal Antibody [PAT26E5AT] (CPAB0234)")
Description
system_update_alt Datasheet
| Product Name: | SHMT1 Antibody |
| Product Sku: | CPAB0234 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human SHMT1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SHMT1 amino acids 1-483 purified from Ecoli. |
| Clone: | PAT26E5AT. |
| Reactivity: | Human |
| Applications: | Western Blot, ELISA, Flow Cytometry |
| Purification Method: | SHMT1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | SHMT1 is a member of the SHMT family. SHMT1 is the cellular form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme which catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5 10-methylene tetrahydrofolate. In addition, SHMT1 specifically provides one-carbon units for thymidylate biosynthesis, reduces methylenetetrahydrofolate pools for S-adenosylmethionine (SAM) synthesis by synthesizing serine, sequesters 5-methyltetrahydrofolate and inhibits SAM synthesis. |
| Synonyms: | Serine hydroxymethyltransferase 1 (soluble), CSHMT, Glycine hydroxymethyltransferase, Serine methylase, 14 kDa protein, cytoplasmic serine hydroxymethyltransferase, serine hydroxymethyltransferase cytosolic, EC 2.1.2.1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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