Description
| Antibody Name: | SH3BP1 Antibody (PACO12181) |
| Antibody SKU: | PACO12181 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Human SH3BP1 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | SH3-domain binding protein 1; |
| UniProt Protein Function: | SH3BP1: Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; Adaptor/scaffold; GAPsChromosomal Location of Human Ortholog: 22q13.1Molecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9Y3L3 |
| NCBI GenInfo Identifier: | 51338841 |
| NCBI Gene ID: | 23616 |
| NCBI Accession: | Q9Y3L3.3 |
| UniProt Secondary Accession: | Q9Y3L3,Q5R3N0, Q6IBZ2, Q6ZVL9, Q96HQ5, Q9NSQ9 |
| UniProt Related Accession: | Q9Y3L3 |
| Molecular Weight: | 50,820 Da |
| NCBI Full Name: | SH3 domain-binding protein 1 |
| NCBI Synonym Full Names: | SH3 domain binding protein 1 |
| NCBI Official Symbol: | SH3BP1 |
| NCBI Official Synonym Symbols: | ARHGAP43 |
| NCBI Protein Information: | SH3 domain-binding protein 1 |
| UniProt Protein Name: | SH3 domain-binding protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | SH3 domain-binding protein |
| UniProt Gene Name: | SH3BP1 |
| UniProt Entry Name: | 3BP1_HUMAN |