Description
| Product Name: | SH2D1B Polyclonal Antibody |
| Product Code: | CAB5125 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:200-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001 [PubMed 11689425]).
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-132 of human SH2D1B (NP_444512.2). |
| Sequence: | MDLPY YHGRL TKQDC ETLLL KEGVD GNFLL RDSES IPGVL CLCVS FKNIV YTYRI FREKH GYYRI QTAEG SPKQV FPSLK ELISK FEKPN QGMVV HLLKP IKRTS PSLRW RGLKL ELETF VNSNS DYVDV LP |
| Synonyms: | EAT2 |
| Calculated MW: | 15kDa |
| Observed MW: | Refer to figures |