SGTA Monoclonal Antibody [PAT19E8AT] (CPAB0651)
![SGTA Monoclonal Antibody [PAT19E8AT] (CPAB0651)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58871/64053/assay-genie-box-4__76760.1706535244.jpg?c=1 "SGTA Monoclonal Antibody [PAT19E8AT] (CPAB0651)")
- SKU:
- CPAB0651
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT19E8AT
- Applications:
- ELISA
- Applications:
- FC
![SGTA Monoclonal Antibody [PAT19E8AT] (CPAB0651)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58871/64053/assay-genie-box-4__76760.1706535244.jpg?c=1&imbypass=on "SGTA Monoclonal Antibody [PAT19E8AT] (CPAB0651)")
Description
system_update_alt Datasheet
| Product Name: | SGTA Antibody |
| Product Sku: | CPAB0651 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human SGTA mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SGTA protein 1-313 amino acids purified from Ecoli. |
| Clone: | PAT19E8AT. |
| Reactivity: | Other bodies |
| Applications: | ELISA, Flow Cytometry |
| Purification Method: | SGTA antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | SGTA is a ubiquitously expressed protein that contains three TPR protein-protein interaction duplicates. SGTA takes part as a component of the androgen receptor (AR)-chaperone-cochaperone complex, functions as a cochaperone and participates in androgen signaling. SGTA binds directly to HSC70 and HSP70 and mediates their ATPase activity. SGTA gene encodes a protein that is able to interact with the chief nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate. In addition, SGTA interacts with Vpu and Gag from HIV-1, SARS-CoV accessory protein 7a, DNAJC5 and DNAJC5B. Since this transcript is expressed universally in several tissues, SGTA serves a housekeeping function. While being involved in apoptosis and androgen signaling, SGTA is a possible molecule for polycystic ovary syndrome, a disorder characterized by androgen excess, obesity and menstrual disturbances. |
| Synonyms: | alphaSGT, hSGT, SGT, Vpu-binding protein, UBP, Small glutamine-rich tetratricopeptide repeat-containing protein alpha, Alpha-SGT, SGT1. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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