SGF29 Antibody (PACO40122)
- SKU:
- PACO40122
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SGF29 Antibody (PACO40122) |
| Antibody SKU: | PACO40122 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human SAGA-associated factor 29 homolog protein (1-293AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO40122 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human spleen tissue using PACO40122 at dilution of 1:100. |
| Background: | Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation. |
| Synonyms: | SAGA-associated factor 29 (Coiled-coil domain-containing protein 101) (SAGA complex-associated factor 29), SGF29, CCDC101 |
| UniProt Protein Function: | CCDC101: Involved in transcriptional regulation, through association with histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. Specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA- type complexes, required to recruit complexes to H3K4me. May be involved in MYC-mediated oncogenic transformation. Belongs to the SGF29 family.Chromosomal Location of Human Ortholog: 16p11.2Molecular Function: methylated histone residue binding; protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | CCDC101 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]).[supplied by OMIM, Apr 2010] |
| UniProt Code: | Q96ES7 |
| NCBI GenInfo Identifier: | 74731608 |
| NCBI Gene ID: | 112869 |
| NCBI Accession: | Q96ES7.1 |
| UniProt Secondary Accession: | Q96ES7,Q96MF5 |
| UniProt Related Accession: | Q96ES7 |
| Molecular Weight: | 33,238 Da |
| NCBI Full Name: | SAGA-associated factor 29 |
| NCBI Synonym Full Names: | SAGA complex associated factor 29 |
| NCBI Official Symbol: | SGF29 |
| NCBI Official Synonym Symbols: | STAF36; TDRD29; CCDC101 |
| NCBI Protein Information: | SAGA-associated factor 29 |
| UniProt Protein Name: | SAGA-associated factor 29 |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 101; SAGA complex-associated factor 29 |
| Protein Family: | |
| UniProt Gene Name: | SGF29 |
| UniProt Entry Name: | SGF29_HUMAN |
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