SFR1 Antibody (PACO59205)
- SKU:
- PACO59205
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SFR1 Antibody (PACO59205) |
| Antibody SKU: | PACO59205 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Swi5-dependent recombination DNA repair protein 1 homolog protein (5-93AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO59205 diluted at 1:200 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Acts as a transcriptional modulator for ESR1. |
| Synonyms: | Swi5-dependent recombination DNA repair protein 1 homolog (Meiosis protein 5 homolog), SFR1, C10orf78 MEI5 MEIR5 |
| UniProt Protein Function: | SFR1: Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Belongs to the SFR1/MEI5 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 10q25.1Cellular Component: nucleusMolecular Function: protein bindingBiological Process: double-strand break repair via homologous recombination |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q86XK3 |
| NCBI GenInfo Identifier: | 50593526 |
| NCBI Gene ID: | 119392 |
| NCBI Accession: | NP_660290 |
| UniProt Secondary Accession: | Q86XK3 |
| UniProt Related Accession: | Q86XK3 |
| Molecular Weight: | 26kDa |
| NCBI Full Name: | swi5-dependent recombination DNA repair protein 1 homolog isoform a |
| NCBI Synonym Full Names: | SWI5 dependent homologous recombination repair protein 1 |
| NCBI Official Symbol: | SFR1 |
| NCBI Official Synonym Symbols: | MEI5; MEIR5; C10orf78; bA373N18.1 |
| NCBI Protein Information: | swi5-dependent recombination DNA repair protein 1 homolog |
| UniProt Protein Name: | Swi5-dependent recombination DNA repair protein 1 homolog |
| UniProt Synonym Protein Names: | Meiosis protein 5 homolog |
| Protein Family: | Swi5-dependent recombination DNA repair protein |
| UniProt Gene Name: | SFR1 |
| UniProt Entry Name: | SFR1_HUMAN |
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