Serpinf1 Antibody (PACO29848)
- SKU:
- PACO29848
- Product Type:
- Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | Serpinf1 Antibody (PACO29848) |
| Antibody SKU: | PACO29848 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Rat |
| Immunogen: | Recombinant Rat Alpha-2 antiplasmin protein (20-418AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | Pigment epithelium-derived factor (PEDF) (Caspin) (Serpin F1) (Stromal cell-derived factor 3) (SDF-3), Serpinf1, Pedf Sdf3 |
| UniProt Protein Function: | PEDF: a secreted neurotrophic protein that induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The N-terminal (AA 44-121) exhibits neurite outgrowth-inducing activity. The C-terminal exposed loop (AA 382-418) is essential for serpin activity. Extracellular phosphorylation enhances antiangiogenic activity. |
| UniProt Protein Details: | Protein type:Inhibitor; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 10q24 Cellular Component: axon; axon hillock; basement membrane; cell soma; extracellular matrix; extracellular region; extracellular space; perinuclear region of cytoplasm Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: aging; kidney development; negative regulation of angiogenesis; negative regulation of inflammatory response; ovulation cycle; positive regulation of neurogenesis; response to acidity; response to arsenic; retina development in camera-type eye; short-term memory |
| NCBI Summary: | mouse homolog is a proteinase inhibitor involved in vascularization [RGD, Feb 2006] |
| UniProt Code: | Q80ZA3 |
| NCBI GenInfo Identifier: | 29293811 |
| NCBI Gene ID: | 287526 |
| NCBI Accession: | NP_808788.1 |
| UniProt Secondary Accession: | Q80ZA3,F1LSW0, |
| Molecular Weight: | 46,465 Da |
| NCBI Full Name: | pigment epithelium-derived factor |
| NCBI Synonym Full Names: | serpin family F member 1 |
| NCBI Official Symbol: | Serpinf1 |
| NCBI Official Synonym Symbols: | Pedf; Dmrs91 |
| NCBI Protein Information: | pigment epithelium-derived factor |
| UniProt Protein Name: | Alpha-2 antiplasmin |
| UniProt Synonym Protein Names: | Alpha-2 antiplasmin |
| UniProt Gene Name: | Serpinf1 |
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