SERPINB11 Antibody (PACO17085)
- SKU:
- PACO17085
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SERPINB11 Antibody (PACO17085) |
| Antibody SKU: | PACO17085 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:10-1:50 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Fusion protein of human SERPINB11 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17085(SERPINB11 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO17085(SERPINB11 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | SerpinB11 (serpin peptidase inhibitor, clade B (ovalbumin), member 11), also known as EPIPIN or SERPIN11, is a 392 amino acid, cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family. Like other members of the serpin family, SerpinB11 has been identified as a noninhibitory intracellular protein. The gene encoding SerpinB11 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Synonyms: | serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene) |
| UniProt Protein Function: | SERPINB11: Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change. Belongs to the serpin family. Ov-serpin subfamily. 3 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 18q21.33Cellular Component: extracellular spaceMolecular Function: serine-type endopeptidase inhibitor activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q96P15 |
| NCBI GenInfo Identifier: | 20140144 |
| NCBI Gene ID: | 89778 |
| NCBI Accession: | Q96P15.1 |
| UniProt Secondary Accession: | Q96P15,Q5Q120, Q5Q121, Q5Q122, Q5Q123, Q6ISD3, Q96P13 Q96P14, A8K9R0 |
| UniProt Related Accession: | Q96P15 |
| Molecular Weight: | 21,080 Da |
| NCBI Full Name: | Serpin B11 |
| NCBI Synonym Full Names: | serpin family B member 11 (gene/pseudogene) |
| NCBI Official Symbol: | SERPINB11 |
| NCBI Official Synonym Symbols: | EPIPIN; SERPIN11 |
| NCBI Protein Information: | serpin B11 |
| UniProt Protein Name: | Serpin B11 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Serpin |
| UniProt Gene Name: | SERPINB11 |
| UniProt Entry Name: | SPB11_HUMAN |
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