Serotonin transporter Monoclonal Antibody
- SKU:
- CAB22413
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | Serotonin transporter Monoclonal Antibody |
| Product Code: | CAB22413 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC50413 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000, IF 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | Cell membrane, Endomembrane system, Endosome membrane, Multi-pass membrane protein |
This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake. There have been conflicting results in the literature about the possible effect, if any, that this polymorphism may play in behavior and depression.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-84 of human Serotonin transporter (NP_001036.1). |
| Sequence: | METTP LNSQK QLSAC EDGED CQENG VLQKV VPTPG DKVES GQISN GYSAV PSPGA GDDTR HSIPA TTTTL VAELH QGERE TWGK |
| Synonyms: | HTT, 5HTT, OCD1, SERT, 5-HTT, SERT1, hSERT, 5-HTTLPR |
| Calculated MW: | 70kDa |
| Observed MW: | Refer to figures |
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