Description
| Antibody Name: | SERINC4 Antibody (PACO20442) |
| Antibody SKU: | PACO20442 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human SERINC4 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20442(SERINC4 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute. |
| Background: | SERINC4 (serine incorporator 4) is a 518 amino acid, multi-pass membrane protein that belongs to the TDE1 family. The SERINC4 protein Incorporates a polar amino acid, serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Because SERINC proteins contain 11 transmembrane segments resembling amino acid, transporters, SERINC4 may also function as an L-serine transporter by carrying serine molecules into the hydrophobic milieu of membrane lipid bilayers. |
| Synonyms: | serine incorporator 4 |
| UniProt Protein Function: | SERINC4: Incorporates a polar amino acid serine into membranes and facilitates the synthesis of two serine-derived lipids, phosphatidylserine and sphingolipids. Belongs to the TDE1 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 15q15.3Cellular Component: integral to membraneMolecular Function: L-serine transmembrane transporter activity |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A6NH21 |
| NCBI GenInfo Identifier: | 189029807 |
| NCBI Gene ID: | 619189 |
| NCBI Accession: | A6NH21.1 |
| UniProt Secondary Accession: | A6NH21,Q3YL75, B2RN41 |
| UniProt Related Accession: | A6NH21 |
| Molecular Weight: | 30,680 Da |
| NCBI Full Name: | Serine incorporator 4 |
| NCBI Synonym Full Names: | serine incorporator 4 |
| NCBI Official Symbol: | SERINC4 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | serine incorporator 4 |
| UniProt Protein Name: | Serine incorporator 4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Serine incorporator |
| UniProt Gene Name: | SERINC4 |
| UniProt Entry Name: | SERC4_HUMAN |
