SERINC3 Antibody (PACO20439)
- SKU:
- PACO20439
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SERINC3 Antibody (PACO20439) |
| Antibody SKU: | PACO20439 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human SERINC3 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 8%SDS-PAGE,Lysate: 40 µg,Lane 1-2: Human right lung cancer tissue, Human left lung cancer tissue,Primary antibody: PACO20439(SERINC3 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 3 minutes. |
| Background: | TDE1, tumor differentially expressed protein 1, is a multi-pass membrane protein also known as serine incorporator 3. Also found on the membranes of the Golgi apparatus within cells, TDE1 is highly expressed in neuronal populations but is also found in thymus, kidney, liver and testis. Expression levels of TDE1 in tumors can be as much as tenfold the amount found in normal tissue of the same type. This increased expression implicates TDE1 as being involved in the cellular transformation from normal to malignant tissue. |
| Synonyms: | serine incorporator 3 |
| UniProt Protein Function: | SERINC3: May be involved in cellular transformation. Belongs to the TDE1 family. |
| UniProt Protein Details: | Protein type:Cell surface; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 20q13.12 Molecular Function:L-serine transmembrane transporter activity Biological Process: defense response to virus; detection of virus; innate immune response |
| UniProt Code: | Q13530 |
| NCBI GenInfo Identifier: | 25453293 |
| NCBI Gene ID: | 10955 |
| NCBI Accession: | Q13530.2 |
| UniProt Secondary Accession: | Q13530,O43717, Q9BR33, B4DUE9, |
| UniProt Related Accession: | Q13530 |
| Molecular Weight: | 46,821 Da |
| NCBI Full Name: | Serine incorporator 3 |
| NCBI Synonym Full Names: | serine incorporator 3 |
| NCBI Official Symbol: | SERINC3 |
| NCBI Official Synonym Symbols: | TDE; TDE1; AIGP1; TMS-1; DIFF33; SBBI99 |
| NCBI Protein Information: | serine incorporator 3 |
| UniProt Protein Name: | Serine incorporator 3 |
| UniProt Synonym Protein Names: | Tumor differentially expressed protein 1 |
| Protein Family: | Serine incorporator |
| UniProt Gene Name: | SERINC3 |
| UniProt Entry Name: | SERC3_HUMAN |
| Antibodies | ELISA Kits |
| SERINC3 Antibody (PACO01601) | SERC3 Colorimetric Cell-Based ELISA |
| SERINC3 Antibody (PACO12103) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
