SENP7 Antibody (PACO17073)
- SKU:
- PACO17073
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SENP7 Antibody (PACO17073) |
| Antibody SKU: | PACO17073 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human SENP7 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 6%SDS-PAGE,Lysate: 40 μg,Lane 1-2: A172 cells, 231 cells,Primary antibody: PACO17073(SENP7 Antibody) at dilution 1/800 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 30 seconds. |
| Background: | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. |
| Synonyms: | SUMO1/sentrin specific peptidase 7 |
| UniProt Protein Function: | Protease that deconjugates SUMO2 and SUMO3 from targeted proteins, but not SUMO1. Catalyzes the deconjugation of poly-SUMO2 and poly-SUMO3 chains. Has very low efficiency in processing full-length SUMO proteins to their mature forms. |
| NCBI Summary: | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for many cellular processes. SUMO-specific proteases, such as SENP7, process SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also display isopeptidase activity for deconjugation of SUMO-conjugated substrates (Lima and Reverter, 2008 [PubMed 18799455]).[supplied by OMIM, Jun 2009] |
| UniProt Code: | Q9BQF6 |
| NCBI GenInfo Identifier: | 300669717 |
| NCBI Gene ID: | 57337 |
| NCBI Accession: | Q9BQF6.4 |
| UniProt Secondary Accession: | Q9BQF6,Q7Z3F4, Q96PS5, Q9C0F6, Q9HBT5, A1L3A5, A8MW39 B7WNW8, |
| UniProt Related Accession: | Q9BQF6 |
| Molecular Weight: | 112,159 Da |
| NCBI Full Name: | Sentrin-specific protease 7 |
| NCBI Synonym Full Names: | SUMO1/sentrin specific peptidase 7 |
| NCBI Official Symbol: | SENP7 |
| NCBI Protein Information: | sentrin-specific protease 7 |
| UniProt Protein Name: | Sentrin-specific protease 7 |
| UniProt Synonym Protein Names: | SUMO-1-specific protease 2; Sentrin/SUMO-specific protease SENP7 |
| Protein Family: | Sentrin-specific protease |
| UniProt Gene Name: | SENP7 |
| UniProt Entry Name: | SENP7_HUMAN |
| Antibodies | ELISA Kits |
| SENP7 Antibody (PACO01482) | SENP7 Colorimetric Cell-Based ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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system_update_altDatasheetHuman SENP7 Recombinant Protein Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rat
