Name: SENP5 Antibody (PACO13604)
SKU: PACO13604
Availability: OutOfStock

Antibody Name:	SENP5 Antibody (PACO13604)
Antibody SKU:	PACO13604
Size:	50ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Human SENP5-Specific

Form:	Liquid
Storage Buffer:	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:	Antigen Affinity purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Synonyms:

SUMO1/sentrin specific peptidase 5;SENP5;DKFZp564O1016;FLJ42398;MGC27076 ;

UniProt Protein Function:	SENP5: Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO3 to its mature form and deconjugation of SUMO2 and SUMO3 from targeted proteins. Has weak proteolytic activity against full-length SUMO1 or SUMO1 conjugates. Required for cell division. Belongs to the peptidase C48 family.
UniProt Protein Details:	Protein type:Nucleolus; Protease; EC 3.4.22.68 Chromosomal Location of Human Ortholog: 3q29 Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleoplasm; nucleus Molecular Function:endopeptidase activity; protein binding; SUMO-specific protease activity Biological Process: protein desumoylation; protein sumoylation
NCBI Summary:	The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP5, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]
UniProt Code:	Q96HI0
NCBI GenInfo Identifier:	296452962
NCBI Gene ID:	205564
NCBI Accession:	Q96HI0.3
UniProt Secondary Accession:	Q96HI0,Q96SA5, B4DY82,
UniProt Related Accession:	Q96HI0
Molecular Weight:	81,310 Da
NCBI Full Name:	Sentrin-specific protease 5
NCBI Synonym Full Names:	SUMO1/sentrin specific peptidase 5
NCBI Official Symbol:	SENP5
NCBI Protein Information:	sentrin-specific protease 5
UniProt Protein Name:	Sentrin-specific protease 5
UniProt Synonym Protein Names:	Sentrin/SUMO-specific protease SENP5
Protein Family:	Sentrin-specific protease
UniProt Gene Name:	SENP5
UniProt Entry Name:	SENP5_HUMAN