SEMG1 Polyclonal Antibody
- SKU:
- CAB24532
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | SEMG1 Polyclonal Antibody |
| Product Code: | CAB24532 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:100-1:500 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | 293T-SEMG1-His(C) |
| Cellular Location: | Secreted |
The protein encoded by this gene is the predominant protein in semen. The encoded secreted protein is involved in the formation of a gel matrix that encases ejaculated spermatozoa. This preproprotein is proteolytically processed by the prostate-specific antigen (PSA) protease to generate multiple peptide products that exhibit distinct functions. One of these peptides, SgI-29, is an antimicrobial peptide with antibacterial activity. This proteolysis process also breaks down the gel matrix and allows the spermatozoa to move more freely. This gene and another similar semenogelin gene are present in a gene cluster on chromosome 20.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 312-462 of human SEMG1 (NP_002998.1). |
| Sequence: | SSIYS QTEEK AQGKS QKQIT IPSQE QEHSQ KANKI SYQSS STEER RLHYG ENGVQ KDVSQ RSIYS QTEKL VAGKS QIQAP NPKQE PWHGE NAKGE SGQST NREQD LLSHE QKGRH QHGSH GGLDI VIIEQ EDDSD RHLAQ HLNND RNPLF T |
| Synonyms: | SEMG1, CT103, SEMG, SGI, dJ172H20.2, semenogelin-1 |
| Calculated MW: | 45kDa/52kDa |
| Observed MW: | 62kDa |
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