Description
Antibody Name: | SEMA3D Antibody (PACO18887) |
Antibody SKU: | PACO18887 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
Species Reactivity: | Human, Mouse |
Immunogen: | Synthetic peptide of human SEMA3D |
Form: | Liquid |
Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification Method: | Antigen affinity purification |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO18887(SEMA3D Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO18887(SEMA3D Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
Background: | This gene Belongs to the semaphorin family. Induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Strong binding to neuropilin is mediated by the carboxy third of the protein. |
Synonyms: | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
UniProt Protein Function: | SEMA3D: a secreted protein that induces the collapse and paralysis of neuronal growth cones. Could potentially act as repulsive cues toward specific neuronal populations. Binds to neuropilin.Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 7q21.11Cellular Component: extracellular spaceMolecular Function: chemorepellent activity; semaphorin receptor bindingBiological Process: negative chemotaxis; negative regulation of axon extension involved in axon guidance; neural crest cell migration; positive regulation of cell migration |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | O95025 |
NCBI GenInfo Identifier: | 8134693 |
NCBI Gene ID: | 223117 |
NCBI Accession: | O95025.2 |
UniProt Secondary Accession: | O95025,Q6UW77, Q8NCQ1, A6NK46 |
UniProt Related Accession: | O95025 |
Molecular Weight: | 89,651 Da |
NCBI Full Name: | Semaphorin-3D |
NCBI Synonym Full Names: | semaphorin 3D |
NCBI Official Symbol: | SEMA3D |
NCBI Official Synonym Symbols: | coll-2; Sema-Z2 |
NCBI Protein Information: | semaphorin-3D |
UniProt Protein Name: | Semaphorin-3D |
UniProt Synonym Protein Names: | |
Protein Family: | Semaphorin |
UniProt Gene Name: | SEMA3D |
UniProt Entry Name: | SEM3D_HUMAN |