SEC24A Antibody (PACO12083)
- SKU:
- PACO12083
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SEC24A Antibody (PACO12083) |
| Antibody SKU: | PACO12083 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human SEC24A |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | SEC24 family, member A (S. cerevisiae); |
| UniProt Protein Function: | SEC24A: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. SEC24A is capable of forming heterodimers with SEC24B and SEC24C. Interacts with TMED2. Expressed in fibroblasts, hepatocytes, and lymphocytes. Belongs to the SEC23/SEC24 family. SEC24 subfamily. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 5q31.1Cellular Component: cytosol; endoplasmic reticulum membraneMolecular Function: protein bindingBiological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; antigen processing and presentation of peptide antigen via MHC class I; COPII coating of Golgi vesicle; ER to Golgi vesicle-mediated transport |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene belongs to a family of proteins that are homologous to yeast Sec24. This protein is a component of coat protein II (COPII)-coated vesicles that mediate protein transport from the endoplasmic reticulum. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the golgi complex. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] |
| UniProt Code: | O95486 |
| NCBI GenInfo Identifier: | 160331913 |
| NCBI Gene ID: | 10802 |
| NCBI Accession: | O95486.2 |
| UniProt Secondary Accession: | O95486,Q8WUV2, Q96GP7, A8MVW3 |
| UniProt Related Accession: | O95486 |
| Molecular Weight: | 66,010 Da |
| NCBI Full Name: | Protein transport protein Sec24A |
| NCBI Synonym Full Names: | SEC24 homolog A, COPII coat complex component |
| NCBI Official Symbol: | SEC24A |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | protein transport protein Sec24A |
| UniProt Protein Name: | Protein transport protein Sec24A |
| UniProt Synonym Protein Names: | SEC24-related protein A |
| Protein Family: | Protein transport protein |
| UniProt Gene Name: | SEC24A |
| UniProt Entry Name: | SC24A_HUMAN |
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