Name: SCUBE1 Antibody (PACO60208)
SKU: PACO60208
Availability: OutOfStock

Antibody Name:	SCUBE1 Antibody (PACO60208)
Antibody SKU:	PACO60208
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, IF:1:50-1:200
Species Reactivity:	Human
Immunogen:	Recombinant Human Signal peptide, CUB and EGF-like domain-containing protein 1 protein (453-566AA)

Form:	Liquid
Storage Buffer:	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method:	>95%, Protein G purified
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

Immunofluorescence staining of Hela cells with PACO60208 at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Background:	Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
Synonyms:	Signal peptide, CUB and EGF-like domain-containing protein 1, SCUBE1

UniProt Protein Function:	SCUBE1: Could function as an adhesive molecule and its matrix bound and soluble fragments may play a critical role in vascular biology.
UniProt Protein Details:	Chromosomal Location of Human Ortholog: 22q13 Cellular Component: extrinsic to plasma membrane; extracellular space; cell surface; external side of plasma membrane Molecular Function:identical protein binding; protein heterodimerization activity; calcium ion binding Biological Process: adult heart development; endothelial cell differentiation; blood coagulation; inflammatory response; protein homooligomerization; post-embryonic development
NCBI Summary:	This gene encodes a cell surface glycoprotein that is a member of the SCUBE (signal peptide, CUB domain, EGF (epidermal growth factor)-like protein) family. Family members have an amino-terminal signal peptide, nine copies of EGF-like repeats and a CUB domain at the carboxyl terminus. This protein is expressed in platelets and endothelial cells and may play an important role in vascular biology. [provided by RefSeq, Oct 2011]
UniProt Code:	Q8IWY4
NCBI GenInfo Identifier:	120587029
NCBI Gene ID:	80274
NCBI Accession:	NP_766638
UniProt Secondary Accession:	Q8IWY4,Q5R336,
UniProt Related Accession:	Q8IWY4
Molecular Weight:	107,910 Da
NCBI Full Name:	signal peptide, CUB and EGF-like domain-containing protein 1
NCBI Synonym Full Names:	signal peptide, CUB domain, EGF-like 1
NCBI Official Symbol:	SCUBE1
NCBI Protein Information:	signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide-CUB domain-EGF-related 1
UniProt Protein Name:	Signal peptide, CUB and EGF-like domain-containing protein 1
Protein Family:	Signal peptide, CUB and EGF-like domain-containing protein
UniProt Gene Name:	SCUBE1
UniProt Entry Name:	SCUB1_HUMAN