SCOC Antibody (PACO29776)
- SKU:
- PACO29776
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SCOC Antibody (PACO29776) |
| Antibody SKU: | PACO29776 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Short coiled-coil protein (1-121AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO29776 at dilution of 1:100. |
 | Immunofluorescence staining of HepG2 cells with PACO29776 at 1:266, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO29776 at dilution of 1:100. |
| Background: | Positive regulator of amino acid, starvation-induced autophagy. |
| Synonyms: | Short coiled-coil protein, SCOC, SCOCO |
| UniProt Protein Function: | SCOC: Positive regulator of amino acid starvation-induced autophagy. Belongs to the SCOC family. 4 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 4q31.1Cellular Component: cytosol; endosome; Golgi membrane; trans-Golgi networkMolecular Function: protein bindingBiological Process: positive regulation of macroautophagy |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a short coiled-coiled domain-containing protein that localizes to the Golgi apparatus. The encoded protein interacts with ADP-ribosylation factor-like proteins. Pseudogenes of this gene are found on chromosomes 1 and 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] |
| UniProt Code: | Q9UIL1 |
| NCBI GenInfo Identifier: | 226528258 |
| NCBI Gene ID: | 60592 |
| NCBI Accession: | NP_001146918.1 |
| UniProt Secondary Accession: | Q9UIL1,Q6P5T9, Q7L2Y0, Q7Z4P2, Q96JY9, Q9BZB2, B7WPH7 D3DNY7, E9PB65 |
| UniProt Related Accession: | Q9UIL1 |
| Molecular Weight: | 14,801 Da |
| NCBI Full Name: | short coiled-coil protein isoform 4 |
| NCBI Synonym Full Names: | short coiled-coil protein |
| NCBI Official Symbol: | SCOC |
| NCBI Official Synonym Symbols: | SCOCO; UNC-69; HRIHFB2072 |
| NCBI Protein Information: | short coiled-coil protein |
| UniProt Protein Name: | Short coiled-coil protein |
| UniProt Synonym Protein Names: | |
| Protein Family: | SCOCO-like protein |
| UniProt Gene Name: | SCOC |
| UniProt Entry Name: | SCOC_HUMAN |
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