SCN4A Antibody (PACO04988)
- SKU:
- PACO04988
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SCN4A Antibody |
| Antibody SKU: | PACO04988 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | WB:1:500-1:2000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | synthesized peptide derived from the Internal region of human Na+ CP type IValpha. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | SCN4A; Sodium channel protein type 4 subunit alpha; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4 |
| UniProt Protein Function: | This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle. |
| NCBI Summary: | Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P35499 |
| NCBI GenInfo Identifier: | 93587342 |
| NCBI Gene ID: | 6329 |
| NCBI Accession: | NP_000325.4 |
| UniProt Secondary Accession: | P35499,Q15478, Q16447, Q7Z6B1, |
| UniProt Related Accession: | P35499 |
| Molecular Weight: | 208 kDa |
| NCBI Full Name: | sodium channel protein type 4 subunit alpha |
| NCBI Synonym Full Names: | sodium voltage-gated channel alpha subunit 4 |
| NCBI Official Symbol: | SCN4A |
| NCBI Official Synonym Symbols: | HYPP; SkM1; CMS16; HYKPP; NAC1A; HOKPP2; Nav1.4; Na(V)1.4 |
| NCBI Protein Information: | sodium channel protein type 4 subunit alpha |
| UniProt Protein Name: | Sodium channel protein type 4 subunit alpha |
| UniProt Synonym Protein Names: | SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4 |
| Protein Family: | Sodium channel protein |
| UniProt Gene Name: | SCN4A |
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