SCML2 Antibody (PACO61249)
- SKU:
- PACO61249
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SCML2 Antibody (PACO61249) |
| Antibody SKU: | PACO61249 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:500-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Sex comb on midleg-like protein 2 protein (466-620AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO61249 diluted at 1:500 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). |
| Synonyms: | Sex comb on midleg-like protein 2, SCML2 |
| UniProt Protein Function: | SCML2: a protein of unknown function. Contains a SAM (sterile alpha motif) and two MBT domains.Protein type: Transcription factorChromosomal Location of Human Ortholog: Xp22Cellular Component: nucleus; PcG protein complexMolecular Function: DNA binding; transcription factor activityBiological Process: anatomical structure morphogenesis |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the Polycomb group proteins. These proteins form the Polycomb repressive complexes which are involved in transcriptional repression. The encoded protein binds histone peptides that are monomethylated at lysine residues and may be involved in regulating homeotic gene expression during development. [provided by RefSeq, Jun 2010] |
| UniProt Code: | Q9UQR0 |
| NCBI GenInfo Identifier: | 47117338 |
| NCBI Gene ID: | 10389 |
| NCBI Accession: | Q9UQR0.1 |
| UniProt Secondary Accession: | Q9UQR0,Q5JXE6, Q86U98, Q8IWD0, Q8NDP2, Q9UGC5 |
| UniProt Related Accession: | Q9UQR0 |
| Molecular Weight: | 15,471 Da |
| NCBI Full Name: | Sex comb on midleg-like protein 2 |
| NCBI Synonym Full Names: | sex comb on midleg-like 2 (Drosophila) |
| NCBI Official Symbol: | SCML2 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | sex comb on midleg-like protein 2 |
| UniProt Protein Name: | Sex comb on midleg-like protein 2 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Sex comb on midleg-like protein |
| UniProt Gene Name: | SCML2 |
| UniProt Entry Name: | SCML2_HUMAN |
| Antibodies |
| SCML2 Antibody (PACO01819) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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