SCAMP4 Antibody (PACO40066)
- SKU:
- PACO40066
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | SCAMP4 Antibody (PACO40066) |
| Antibody SKU: | PACO40066 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Secretory carrier-associated membrane protein 4 protein (170-228AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human breast cancer using PACO40066 at dilution of 1:100. |
 | Immunofluorescent analysis of U251 cells using PACO40066 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Probably involved in membrane protein trafficking. |
| Synonyms: | Secretory carrier-associated membrane protein 4 (Secretory carrier membrane protein 4), SCAMP4 |
| UniProt Protein Function: | SCAMP4: Probably involved in membrane protein trafficking. Belongs to the SCAMP family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, multi-pass; Membrane protein, integral; VesicleChromosomal Location of Human Ortholog: 19p13.3Cellular Component: integral to membraneBiological Process: protein transport |
| UniProt Protein Details: | |
| NCBI Summary: | Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011] |
| UniProt Code: | Q969E2 |
| NCBI GenInfo Identifier: | 17738287 |
| NCBI Gene ID: | 113178 |
| NCBI Accession: | NP_524558.1 |
| UniProt Secondary Accession: | Q969E2,Q8N2N1, Q8NAV0 |
| UniProt Related Accession: | Q969E2 |
| Molecular Weight: | 25,728 Da |
| NCBI Full Name: | secretory carrier-associated membrane protein 4 |
| NCBI Synonym Full Names: | secretory carrier membrane protein 4 |
| NCBI Official Symbol: | SCAMP4 |
| NCBI Official Synonym Symbols: | SCAMP-4 |
| NCBI Protein Information: | secretory carrier-associated membrane protein 4 |
| UniProt Protein Name: | Secretory carrier-associated membrane protein 4 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Secretory carrier-associated membrane protein |
| UniProt Gene Name: | SCAMP4 |
| UniProt Entry Name: | SCAM4_HUMAN |
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