Description
| Antibody Name: | SAMD4A Antibody (PACO20385) |
| Antibody SKU: | PACO20385 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human SAMD4A |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO20385(SAMD4A Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20385(SAMD4A Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | Sterile α motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein. |
| Synonyms: | sterile α motif domain containing 4A |
| UniProt Protein Function: | Function: Acts as a translational repressor of SRE-containing messengers. Ref.6Subcellular location: Cytoplasm. Cell projection dendrite By similarity. Cell junction synapse synaptosome By similarity. Note: Enriched in synaptoneurosomes By similarity. Shuttles between the nucleus and the cytoplasm in a CRM1-dependent manner. Colocalizes throughout the cytoplasm in granules with polyadenylated RNAs, PABPC1 and STAU1. Also frequently colocalizes in cytoplasmic stress granule-like foci with ELAVL1, TIA1 and TIAL1. Ref.6Sequence similarities: Belongs to the SMAUG family.Contains 1 SAM (sterile alpha motif) domain.Sequence caution: The sequence AAH57838.1 differs from that shown. Reason: Intron retention.The sequence AAP97302.1 differs from that shown. Reason: Intron retention. |
| UniProt Protein Details: | |
| NCBI Summary: | Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein (Baez and Boccaccio, 2005 [PubMed 16221671]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9UPU9 |
| NCBI GenInfo Identifier: | 1708342410 |
| NCBI Gene ID: | 23034 |
| NCBI Accession: | NM_015589.6 |
| UniProt Secondary Accession: | Q9UPU9 |
| UniProt Related Accession: | Q9UPU9 |
| Molecular Weight: | |
| NCBI Full Name: | Homo sapiens sterile alpha motif domain containing 4A (SAMD4A), transcript variant 1, mRNA |
| NCBI Synonym Full Names: | sterile alpha motif domain containing 4A |
| NCBI Official Symbol: | SAMD4A |
| NCBI Official Synonym Symbols: | SMG; SMGA; SAMD4; SMAUG; SMAUG1 |
| NCBI Protein Information: | protein Smaug homolog 1 |
| UniProt Protein Name: | Protein Smaug homolog 1 |
| UniProt Synonym Protein Names: | Sterile alpha motif domain-containing protein 4A |
| Protein Family: | Protein |
| UniProt Gene Name: | SAMD4A |
| UniProt Entry Name: | SMAG1_HUMAN |
| Antibodies |
| SAMD4A Antibody (PACO12019) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |

