S100A7/Psoriasin Polyclonal Antibody
- SKU:
- CAB22026
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IHC
Description
| Product Name: | S100A7/Psoriasin Polyclonal Antibody |
| Product Code: | CAB22026 |
| Reactivity: | Human |
| Applications: | Western blotting, Immunohistochemistry |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, IHC-P, ELISA |
| Key Applications: | Western blotting, Immunohistochemistry |
| Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | SK-BR-3 |
| Cellular Location: | cytoplasm, cytosol, endoplasmic reticulum, extracellular region, extracellular space, focal adhesion, nucleus |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-101 of human S100A7/Psoriasin (NP_002954.2). |
| Sequence: | SNTQA ERSII GMIDM FHKYT RRDDK IEKPS LLTMM KENFP NFLSA CDKKG TNYLA DVFEK KDKNE DKKID FSEFL SLLGD IATDY HKQSH GAAPC SGGSQ |
| Synonyms: | PSOR1, S100A7c |
| Calculated MW: | 11kDa |
| Observed MW: | 12kDa |
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