Description
Product Name: | S100A7/Psoriasin Monoclonal Antibody |
Product Code: | CAB22271 |
Reactivity: | Human |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC56869 |
Reactivity: | Human |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:1000-1:5000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | SK-BR-3 |
Cellular Location: | Cytoplasm, Secreted |
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2-101 of human S100A7/Psoriasin (NP_002954.2). |
Sequence: | SNTQA ERSII GMIDM FHKYT RRDDK IEKPS LLTMM KENFP NFLSA CDKKG TNYLA DVFEK KDKNE DKKID FSEFL SLLGD IATDY HKQSH GAAPC SGGSQ |
Synonyms: | PSOR1, S100A7c |
Calculated MW: | 11kDa |
Observed MW: | 12kDa |